September 10th, 2026

2026 DFCI-TPD In Person Meeting

12.00 – 12.30 pm Arrival, Registration and Boxed lunch​

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12:30 – 12:40 pm  Welcome Remarks

Dana-Farber Targeted Protein Degradation Organizing Committee Mikołaj Słabicki, Katherine Donovan

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12:40 – 1:40 pm    Keynote: Jay Bradner, AMGEN, host: Katherine Donovan

Therapeutic Modularity | Induced Proximity Therapeutics

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1:40 – 2:10 pm     William Gibson, Dana-Farber Cancer Institute, host: Hubert Huang

TBC

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2:10 – 2:40 pm     Yufei Xu, Astellas, host: John Che

Discovery of KRAS Degraders and Expansion of TPD to Challenging Targets

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2:40 – 3:10 pm    Radek Nowak, University of Bonn, host: Mikołaj Słabicki

Targeting transcription factors for degradation

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3:10 – 3:40 pm    Light snack / Coffee break

3:40 – 4:10 pm    Sara Buhrlage, Dana-Farber Cancer Institute, host: Breanna Zerfas

Pharmacologic interrogation of USP28 cellular function in p53 signaling reveals new therapeutic opportunity

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4:10 – 4:40 pm    Michael Erb, Scripps, host: Hubert Huang

Rewiring DNA repair with PARP-based chemical inducers of proximity

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4:40 – 5:10 pm    Samuel Ojeda, Dana-Farber Cancer Institute, host: Sean Gao

Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues

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5:10 – 5:40 pm   Daniel La, Triana, host: Breanna Zerfas

Discovery of TRI-611, a Selective, CNS-Penetrant Molecular Glue Degrader for ALK-Positive NSCLC

5:40 – 7:00 pm    Reception (Appetizers and Open Bar)

Event Location:  Linda K. Paresky Conference Center, Simmons University 300 Fenway Boston, MA 02115.

There is a limited number of registration slots available and is based on the seminar room capacity. Registration will work on a first come first served basis. Registration is free of charge, but please cancel your registration (drop line to DFCI.TPD@gmail.com) if you cannot join to open space for others.

Event organized by:

Dana-Farber Targeted Protein Degradation Organizing Committee
Mikołaj Słabicki, Katherine Donovan, Breanna Zerfas, Hubert Huang, John Che, Sean Gao

Sponsored by: